Amlexanox, TBK1 and IKKepsilon inhibitor (ab142825)
Key features and details
- Selective TBK1 and IKKε inhibitor
- CAS Number: 68302-57-8
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Amlexanox, TBK1 and IKKepsilon inhibitor -
Description
Selective TBK1 and IKKε inhibitor -
Biological description
Selective TBK1 and IKKε inhibitor (IC50 = 1-2 μM). Shows antiallergic, antiobesogenic and anti-inflammatory effects in vivo. Orally active.
-
Purity
> 99% -
CAS Number
68302-57-8 -
Chemical structure
Properties
-
Chemical name
2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid -
Molecular weight
298.30 -
Molecular formula
C16H14N2O4 -
PubChem identifier
2161 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N -
Source
Synthetic
-
Research areas
