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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Amitriptyline hydrochloride, Serotonin and noradrenalin uptake inhibitor (ab141902)

Key features and details

  • Serotonin and noradrenalin uptake inhibitor
  • CAS Number: 549-18-8
  • Purity: > 98%
  • Soluble to 100 mM in water and to 100 mM in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Amitriptyline hydrochloride, Serotonin and noradrenalin uptake inhibitor
  • Description

    Serotonin and noradrenalin uptake inhibitor
  • Biological description

    Serotonin and noradrenalin uptake inhibitor. Tricyclic antidepressant (TCA). Shows antidepressant and antinociceptive activity. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    549-18-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-(5,6-Dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
  • Molecular weight

    313.86
  • Molecular formula

    C20H23N.HCl
  • PubChem identifier

    11065
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble to 100 mM in water and to 100 mM in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Transporters
    • Other
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Potassium Channels
    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Signal Transduction
    • Metabolism
    • Plasma Membrane
    • Channels
    • Cardiovascular
    • Blood
    • Blood Pressure regulation
    • Cardiovascular
    • Vasculature
    • Vasoconstriction
    • Other
    • Cardiovascular
    • Vasculature
    • Vasodilation
    • Other
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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