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alpha-Amanitin, RNA polymerase II inhibitor (ab144512)

Price and availability

174 220 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Mycotoxin. RNA polymerase II inhibitor.
  • CAS Number: 23109-05-9
  • Purity: > 90%
  • Soluble in water, in ethanol to 5 mM and in DMSO
  • Form / State: Solid
  • Source: Amanita sp.

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Overview

  • Product name

    alpha-Amanitin, RNA polymerase II inhibitor
  • Description

    Mycotoxin. RNA polymerase II inhibitor.
  • Biological description

    Potent and selective RNA polymerase II inhibitor. Mycotoxin. mRNA synthesis inhibitor. Shows similar effects to γ-amanitin (ab144514) and β-amanitin (ab144513). Inhibits mammalian protein synthesis in vivo. Orally active.
  • Purity

    > 90%
  • CAS Number

    23109-05-9
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    918.97
  • Molecular formula

    C39H54N10O14S
  • PubChem identifier

    441541
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water, in ethanol to 5 mM and in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H]2CS(=O)C3=C(C[C@@H](C(=O)NCC(=O)N1)NC(=O)[C@@H](NC(=O)[C@@H]4C[C@H](CN4C(=O)[C@@H](NC2=O)CC(=O)N)O)[C@@H](C)[C@H](CO)O)C5=C(N3)C=C(C=C5)O
  • Source

    Amanita sp.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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