ALK Mutant (T1151_L1152insT), Active (ab186465)
Key features and details
- Expression system: Insect cells
- Purity: > 80% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
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Product name
ALK Mutant (T1151_L1152insT), Active
See all ALK proteins and peptides -
Biological activity
Specific activity of ab186465 was determined to be 13 nmol/min/mg as per activity assay protocol.
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Purity
> 80 % Densitometry. -
Expression system
Insect cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
RRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLK EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKLPEVCSEQD ELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE TRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKT DTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYR IMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEK VPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAE ISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSW FTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPS SLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILK SKNSMNQPGP -
Predicted molecular weight
90 kDa including tags -
Amino acids
1060 to 1620 -
Modifications
unmodified -
Tags
GST tag N-Terminus -
Additional sequence information
Cytoplasmic domain ALK Mutant (T1151_L1152insT)
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Preparation and Storage
- Alk
- ALK tyrosine kinase receptor
- ALK/EML4 fusion gene, included
Images
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The specific activity of ALK (ab186465) was determined to be 49 nmol/min/mg as per activity assay protocol and was equivalent to 200 nmol/min/mg as per radiometric assay
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SDS PAGE analysis of ab186465
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SDS PAGE analysis of ab186465
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Specific activity of ab186465 was determined to be 13 nmol/min/mg as per activity assay protocol.
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Purity of ab186465 was determined to be >80% by densitometry. Approx. MW 90kDa.