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Neuroscience Neurotransmission Intracellular Signaling Kinases

ALK Mutant (T1151_L1152insT), Active (ab186465)

ALK Mutant (T1151_L1152insT), Active (ab186465)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Insect cells
  • Purity: > 80% Densitometry
  • Active: Yes
  • Tags: GST tag N-Terminus
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    ALK Mutant (T1151_L1152insT), Active
    See all ALK proteins and peptides
  • Biological activity

    Specific activity of ab186465 was determined to be 13 nmol/min/mg as per activity assay protocol.

  • Purity

    > 80 % Densitometry.

  • Expression system

    Insect cells
  • Accession

    Q9UM73
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      RRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLK EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKLPEVCSEQD ELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE TRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKT DTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYR IMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEK VPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAE ISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSW FTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPS SLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILK SKNSMNQPGP
    • Predicted molecular weight

      90 kDa including tags
    • Amino acids

      1060 to 1620
    • Modifications

      unmodified
    • Tags

      GST tag N-Terminus
    • Additional sequence information

      Cytoplasmic domain ALK Mutant (T1151_L1152insT)

Preparation and Storage

  • Alk
  • ALK tyrosine kinase receptor
  • ALK/EML4 fusion gene, included

Images

  • Functional Studies - ALK Mutant (T1151_L1152insT), Active (ab186465)
    Functional Studies - ALK Mutant (T1151_L1152insT), Active (ab186465)
    The specific activity of ALK (ab186465) was determined to be 49 nmol/min/mg as per activity assay protocol and was equivalent to 200 nmol/min/mg as per radiometric assay
  • SDS-PAGE - ALK Mutant (T1151_L1152insT), Active (ab186465)
    SDS-PAGE - ALK Mutant (T1151_L1152insT), Active (ab186465)
    SDS PAGE analysis of ab186465
  • SDS-PAGE - ALK Mutant (T1151_L1152insT), Active (ab186465)
    SDS-PAGE - ALK Mutant (T1151_L1152insT), Active (ab186465)
    SDS PAGE analysis of ab186465
  • Functional Studies - ALK Mutant (T1151_L1152insT), Active (ab186465)
    Functional Studies - ALK Mutant (T1151_L1152insT), Active (ab186465)

    Specific activity of ab186465 was determined to be 13 nmol/min/mg as per activity assay protocol.

  • SDS-PAGE - ALK Mutant (T1151_L1152insT), Active (ab186465)
    SDS-PAGE - ALK Mutant (T1151_L1152insT), Active (ab186465)

    Purity of ab186465 was determined to be >80% by densitometry. Approx. MW 90kDa.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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