AK-1, SIRT2 inhibitor (ab144549)
Key features and details
- Cell-permeable SIRT2 inhibitor
- CAS Number: 330461-64-8
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AK-1, SIRT2 inhibitor -
Description
Cell-permeable SIRT2 inhibitor -
Biological description
Cell-permeable SIRT2 inhibitor (IC50 = 13 μM). Increases acetylated tubulin levels. Shows neuroprotective effects in vivo.
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Purity
> 99% -
CAS Number
330461-64-8 -
Chemical structure
Properties
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Chemical name
3-[(Hexahydro-1H-azepin-1-yl)sulfonyl]-N-(3-nitrophenyl)benzamide -
Molecular weight
403.45 -
Molecular formula
C19H21N3O5S -
PubChem identifier
1341463 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=S(=O)(c1cc(ccc1)C(=O)Nc2cccc(c2)[N+]([O-])=O)N3CCCCCC3 -
Source
Synthetic
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Research areas
