AAL 993, VEGFR inhibitor (ab141590)
Key features and details
- Potent, selective and cell-permeable VEGFR inhibitor
- CAS Number: 269390-77-4
- Purity: > 98%
- Soluble in ethanol to 25 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
AAL 993, VEGFR inhibitor -
Description
Potent, selective and cell-permeable VEGFR inhibitor -
Biological description
Potent, selective and cell-permeable VEGFR inhibitor (IC50 values are 130, 23 and 18 nM for VEGFR1, 2, and 3 respectively). Inhibits VEGF-induced angiogenesis in vivo. Suppresses hypoxia-induced HIF-1α expression without affecting Akt phosphorylation in vitro.
-
Purity
> 98% -
CAS Number
269390-77-4 -
Chemical structure
