AACOCF3 (Arachidonyl trifluoromethyl ketone), Phospholipase-A2 inhibitor (ab120350)
Key features and details
- Phospholipase-A2 inhibitor
- CAS Number: 149301-79-1
- Supplied in ethanol (5 mg/ml)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
AACOCF3 (Arachidonyl trifluoromethyl ketone), Phospholipase-A2 inhibitor -
Description
Phospholipase-A2 inhibitor -
Alternative names
- Arachidonyl trifluoromethyl ketone
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Biological description
Cell-permeable analog of arachidonic acid (ab120916). Widely used as an inhibitor of the 85-kDa cytosolic group IV phospholipase A2 (cPLA2) and calcium-independent group VI phospholipase A2 (iPLA2) (IC50 values are 1.5 and 6.0 μM, respectively) . In non-neural cells, also inhibits cyclooxygenase and acyltransferase activities.
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CAS Number
149301-79-1 -
Chemical structure
Properties
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Chemical name
(6Z,9Z,12Z,15Z)-1,1,1-Trifluorohenicosa-6,9,12,15-tetraen-2-one -
Molecular weight
356.47 -
Molecular formula
C21H31F3O -
PubChem identifier
5280436 -
Storage instructions
Store at -20°C. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Supplied in ethanol (5 mg/ml) -
Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
FC(F)(F)C(=O)CCCC=C/C/C=CC/C=CC/C=CCCCCC -
Source
Synthetic
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Research areas
