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Signal Transduction Signaling Pathway Lipid Signaling PLA

ONO-RS-082, phospholipase A2 (PLA2) inhibitor (ab141760)

Key features and details

  • Potent, reversible phospholipase A2 (PLA2) inhibitor
  • CAS Number: 99754-06-0
  • Purity: > 98%
  • Soluble in DMSO to 50 mM (with warming) and in ethanol to 25 mM (with warming)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    ONO-RS-082, phospholipase A2 (PLA2) inhibitor
  • Description

    Potent, reversible phospholipase A2 (PLA2) inhibitor
  • Biological description

    Potent, reversible PLA2 inhibitor (IC50 = 7 µM). Cell-permeable. Active in ex vivo preparations.
  • Purity

    > 98%
  • CAS Number

    99754-06-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Chloro-2-[[(E)-3-(4-pentylphenyl)prop-2-enoyl]amino]benzoic acid
  • Molecular weight

    371.90
  • Molecular formula

    C21H22ClNO3
  • PubChem identifier

    6438389
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO to 50 mM (with warming) and in ethanol to 25 mM (with warming)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCC1=CC=C(C=C1)C=CC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • PLA
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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