α-Methyl-γ-hydroxy-1,N2-propano-2’-deoxyguanosine (Mixture of Diastereomers) (ab144781)
Key features and details
- Genotoxic cyclic adduct of 2'-deoxyguanosine with crotonaldehyde
- CAS Number: 132014-87-0
- Soluble in water and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
α-Methyl-γ-hydroxy-1,N2-propano-2’-deoxyguanosine (Mixture of Diastereomers) -
Description
Genotoxic cyclic adduct of 2'-deoxyguanosine with crotonaldehyde -
Alternative names
- Cr-PdG
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Biological description
Genotoxic cyclic adduct of 2'-deoxyguanosine with crotonaldehyde. Histones accelerate cyclic 1,N2-propanoguanine adduct-formation of DNA. -
CAS Number
132014-87-0 -
Chemical structure
Properties
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Chemical name
8-Hydroxy-3-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methyl-4,6,7,8-tetrahydropyrimido[1,2-a]purin-10-one -
Molecular weight
337.33 -
Molecular formula
C14H19N5O5 -
PubChem identifier
71750391 -
Storage instructions
Store at -20°C. Store In the Dark. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in water and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC(N2C(=O)C3=C(NC2=N1)N(C=N3)[C@H]4CC([C@H](O4)CO)O)O -
Source
Synthetic
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Research areas
