AT 101, Bcl-2 and Mcl-1 inhibitor (BH3-mimetic) (ab145624)
Key features and details
- Pro-apoptotic agent. BH3-mimetic. Bcl-2 and Mcl-1 inhibitor.
- CAS Number: 90141-22-3
- Purity: > 98%
- Soluble in ethanol to 75 mM and in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AT 101, Bcl-2 and Mcl-1 inhibitor (BH3-mimetic) -
Description
Pro-apoptotic agent. BH3-mimetic. Bcl-2 and Mcl-1 inhibitor. -
Biological description
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Purity
> 98% -
CAS Number
90141-22-3 -
Chemical structure
Properties
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Chemical name
(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde -
Molecular weight
518.56 -
Molecular formula
C30H30O8 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 75 mM and in DMSO to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC1=C(O)C(C(C)C)=C(C=C(C)C(C2=C(O)C(C(C([H])=O)=C(O)C(O)=C3C(C)C)=C3C=C2C)=C4O)C4=C1C([H])=O -
Source
Synthetic
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Research areas