A-1331852, BCL-XL inhibitor (ab218112)
Key features and details
- Potent, selective BCL-XL inhibitor
- CAS Number: 1430844-80-6
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
A-1331852, BCL-XL inhibitor -
Description
Potent, selective BCL-XL inhibitor -
Alternative names
- A1331852
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Biological description
Potent, selective BCL-XL inhibitor (Ki L-BIM complexes and induces the hallmarks of apoptosis in BCL-XL-dependent Molt-4 cells.
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Purity
> 99% -
CAS Number
1430844-80-6 -
Chemical structure
Properties
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Chemical name
6-[8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-3-[5-methyl-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazol-4-yl]-2-pyridinecarboxylic acid -
Molecular weight
658.81 -
Molecular formula
C38H38N6O3S -
PubChem identifier
71565985 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=CC=CC(=C7C6)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O -
Source
Synthetic
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Research areas
