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Signal Transduction Signaling Pathway Lipid Signaling PLA

7,7-Dimethyleicosadienoic acid, PLA2 inhibitor (ab141544)

Key features and details

  • PLA2 inhibitor. Arachadonic acid analog.
  • CAS Number: 89560-01-0
  • Purity: > 99%
  • Soluble in ethanol
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    7,7-Dimethyleicosadienoic acid, PLA2 inhibitor
  • Description

    PLA2 inhibitor. Arachadonic acid analog.
  • Biological description

    Phopholipase A2 inhibitor (IC50 = 16 μM). Inhibits COX and lipoxygenase pathways (IC50 values are 56 and 14 μM respectively). Inhibits production of PGE2 (IC50 = 2 μM). Arachadonic acid analog (ab120916). Cell permeable.
  • Purity

    > 99%
  • CAS Number

    89560-01-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (5Z,8Z)-7,7-Dimethylicosa-5,8-dienoic acid
  • Molecular weight

    336.60
  • Molecular formula

    C22H40O2
  • PubChem identifier

    5312331
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCC=CC(C)(C)C=CCCCC(=O)O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • PLA
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Heart disease
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Diabetes
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Hypertension
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Obesity
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Research Area
    • Stroke
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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