4-Hydroxydiclofenac, Diclofenac metabolite (ab145912)
Key features and details
- Diclofenac metabolite. COX2 inhibitor.
- CAS Number: 64118-84-9
- Purity: > 97%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
4-Hydroxydiclofenac, Diclofenac metabolite -
Description
Diclofenac metabolite. COX2 inhibitor. -
Alternative names
- [2-(2,6-Dichloro-4-hydroxy-phenylamino)phenyl]acetic acid
- 4'-Hydroxy Diclofenac
- 4'-OH-DCF
see all -
Biological description
Active 4'-hydroxylated metabolite of diclofenac. Suppresses prostaglandin E2 (PGE2) formation by specifically blocking COX2 activity. Demonstrates anti-inflammatory and analgesic properties.
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Purity
> 97% -
CAS Number
64118-84-9 -
Chemical structure
Properties
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Chemical name
2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic acid -
Molecular weight
312.10 -
Molecular formula
C14H11Cl2NO3 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic