2-Methoxyestradiol, antitumor and antiangiogenic agent (ab120653)
Key features and details
- Potent antitumor and antiangiogenic agent
- CAS Number: 362-07-2
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-Methoxyestradiol, antitumor and antiangiogenic agent -
Description
Potent antitumor and antiangiogenic agent -
Biological description
Potent antioxidant. Inhibits angiogenesis in vivo with direct cytotoxic effects seen in vitro. Interacts with endothelial tubulin dynamics and increases the expression of death receptor 5 in endothelial cells. Induces apoptosis by p53 induction via activation of p38/JNK pathways.
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Purity
> 98% -
CAS Number
362-07-2 -
Chemical structure
