2-(1,8-Naphthyridin-2-ly)phenol, STAT1 transcriptional activator (ab142704)
Key features and details
- Selective STAT1 transcriptional activator. Cell-permeable.
- CAS Number: 65182-56-1
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
2-(1,8-Naphthyridin-2-ly)phenol, STAT1 transcriptional activator -
Description
Selective STAT1 transcriptional activator. Cell-permeable. -
Biological description
Selective STAT1 transcriptional activator. No effect on unrelated transcription factors NF-κB or STAT3. Enhances ability of IFN-γ to inhibit cancer cells in vitro. Antitumor agent. Active in vitro. Cell-permeable. -
Purity
> 98% -
CAS Number
65182-56-1 -
Chemical structure
Properties
-
Chemical name
6-(1H-1,8-Naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one -
Molecular weight
222.24 -
Molecular formula
C14H10N2O -
PubChem identifier
6789423 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1=CC(=C2C=CC3=C(N2)N=CC=C3)C(=O)C=C1 -
Source
Synthetic
-
Research areas