IQ-1S, JNK3 inhibitor (ab146180)
Key features and details
- Selective JNK3 inhibitor
- CAS Number: 23146-22-7
- Soluble in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IQ-1S, JNK3 inhibitor -
Description
Selective JNK3 inhibitor -
Biological description
Selective JNK3 inhibitor (IC50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo. -
CAS Number
23146-22-7 -
Chemical structure
Properties
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Chemical name
11H-Indeno[1,2-b]quinoxalin-11-one oxime -
Molecular weight
247.25 -
Molecular formula
C15H9N3O -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O\N=C2/c4ccccc4c1nc3ccccc3nc12 -
Source
Synthetic
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Research areas
