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Signal Transduction Metabolism Lipid metabolism

14,15-Leukotriene E4 (Eoxin-E4), Mediator of inflammation (ab141698)

Key features and details

  • Mediator of inflammation
  • CAS Number: 1000852-57-2
  • Purity: > 98%
  • Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml)
  • Form / State: Liquid
  • Source: Synthetic

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Overview

  • Product name

    14,15-Leukotriene E4 (Eoxin-E4), Mediator of inflammation
  • Description

    Mediator of inflammation
  • Alternative names

    • 14,15-LTE4
    • Eoxin E4
  • Biological description

    Product of the 15-lipoxygenase (15-LOX) pathway. Shows anti-inflammatory activity. For in vivo and in vitro use.
  • Purity

    > 98%
  • CAS Number

    1000852-57-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (5Z,8Z,10E,12E,14R,15S)-14-[(2R)-2-Amino-2-carboxyethyl]sulfanyl-15-hydroxyicosa-5,8,10,12-tetraenoic acid
  • Molecular weight

    439.61
  • Molecular formula

    C23H37NO5S
  • PubChem identifier

    52921882
  • Storage instructions

    Store at -80°C.
  • Solubility overview

    Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCC(C(C=CC=CC=CCC=CCCCC(=O)O)SCC(C(=O)O)N)O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Oxygenase
    • Lipooxygenase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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