1-Naphthohydroxamic acid, HDAC8 inhibitor (ab144502)
Key features and details
- Potent, cell-permeable and selective HDAC8 inhibitor
- CAS Number: 6953-61-3
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
1-Naphthohydroxamic acid, HDAC8 inhibitor -
Description
Potent, cell-permeable and selective HDAC8 inhibitor -
Alternative names
- Compound 2
- HDAC inhibitor XIX
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Biological description
Potent, cell-permeable and selective histone deacetylase inhibitor (HDAC8) inhibitor (IC50 = 14 μM). Anticancer agent. Active in vitro.
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Purity
> 98% -
CAS Number
6953-61-3 -
Chemical structure
Properties
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Chemical name
1-Naphthohydroxamic acid -
Molecular weight
187.20 -
Molecular formula
C11H9NO2 -
PubChem identifier
23382 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
ONC(=O)c2cccc1ccccc12 -
Source
Synthetic
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Research areas
