Zoledronic acid, FPP synthase inhibitor (ab141980)
Key features and details
- Highly potent bisphosphonate. FPP synthase inhibitor.
- CAS Number: 118072-93-8
- Purity: > 98%
- Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Zoledronic acid, FPP synthase inhibitor -
Description
Highly potent bisphosphonate. FPP synthase inhibitor. -
Biological description
Highly potent bisphosphonate. FPP synthase inhibitor. Inhibits osteoclastogenesis (IC50 = 15 nM). Inhibits ASM and FDPS. Activates PKC. Inhibits osteoclastic bone resorption, shows antihypocalcemic and antiangiogenic effects in vivo. -
Purity
> 98% -
CAS Number
118072-93-8 -
Chemical structure
Properties
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Chemical name
(1-Hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid -
Molecular weight
272.09 -
Molecular formula
C5H10N2O7P2 -
PubChem identifier
68740 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O -
Source
Synthetic
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Research areas
