Zearalenone (ZEA), ERalpha and ERbeta ligand (ab142473)
Key features and details
- Mixed potent, nonsteroidal ERα and ERβ ligand. Mycotoxin.
- CAS Number: 17924-92-4
- Purity: > 98%
- Form / State: Solid
- Source: Fusarium sp.
Overview
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Product name
Zearalenone (ZEA), ERalpha and ERbeta ligand -
Description
Mixed potent, nonsteroidal ERα and ERβ ligand. Mycotoxin. -
Biological description
Mixed potent, nonsteroidal ERα and ERβ ligand (IC50 values are 56 and 41 nM for ERα and ERβ respectively). Shows agonist effects at lower doses. Partially selective for ERα activation. Induces apoptosis in male germ cells. Active in vivo. -
Purity
> 98% -
CAS Number
17924-92-4 -
Chemical structure
Properties
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Chemical name
(2E,11S)-15,17-Dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraene-7,13-dione -
Molecular weight
318.36 -
Molecular formula
C18H22O5 -
PubChem identifier
5281576 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CCCC(=O)CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O -
Source
Fusarium sp.
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Research areas
