Z-FA-FMK, Cysteine protease inhibitor (ab141484)
Key features and details
- Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor.
- CAS Number: 105637-38-5
- Purity: > 95%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Z-FA-FMK, Cysteine protease inhibitor -
Description
Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor. -
Biological description
Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor. Selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Inhibits cathepsin B, L, and S, papain and cruzain. Induces apoptosis and necrosis. Shows anti-inflammatory effects in vivo. Negative control for caspase inhibitors. Liquid form also available (ab141384)
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Purity
> 95% -
CAS Number
105637-38-5 -
Chemical structure
Properties
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Chemical name
Benzyl N-[1-[(4-fluoro-3-oxobutan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate -
Molecular weight
386.42 -
Molecular formula
C21H23N2O4F -
PubChem identifier
122019 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2 -
Source
Synthetic
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Research areas
