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Cancer Invasion/microenvironment Apoptosis Caspases

Z-ATAD-FMK, Caspase-12 inhibitor (ab141383)

Key features and details

  • Caspase-12 inhibitor
  • CAS Number:
  • Purity: > 95%
  • Soluble in DMSO to 20 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Z-ATAD-FMK, Caspase-12 inhibitor
  • Description

    Caspase-12 inhibitor
  • Biological description

    Specific caspase-12 inhibitor. Suppresses annular cell apoptosis and caspase-9 activity in vitro. Active in vitro and in vivo.
  • Purity

    > 95%
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    540.54
  • Molecular formula

    C24H33N4O9F
  • Sequence

    ATAD (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK; Asp-4 = Asp(OMe))
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 20 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Intracellular
    • Caspases etc
    • Caspases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Chemical Type
    • Bioactive peptides
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Caspase
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Heart disease
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Smoothened
    • Biochemicals
    • Research Area
    • Cancer
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Diabetes
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Diabetes
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Diabetes
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Smoothened
    • Biochemicals
    • Research Area
    • Heart disease
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Hypertension
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Hypertension
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Hypertension
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Smoothened
    • Biochemicals
    • Research Area
    • Obesity
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Obesity
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Obesity
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Smoothened
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Stroke
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Stroke
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Research Area
    • Stroke
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Smoothened

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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