VU 0238429, allosteric M5 modulator (ab141307)
Key features and details
- Selective, positive allosteric M5 modulator
- CAS Number: 1160247-92-6
- Purity: > 99%
- Soluble in DMSO to 100 mM and ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
VU 0238429, allosteric M5 modulator -
Description
Selective, positive allosteric M5 modulator -
Biological description
Selective, positive allosteric M5 modulator (EC50 values are 1.16 and >30 μM at M5 and M1/ M3 receptors, respectively). Shows no activity at M2 and M4 receptors.
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Purity
> 99% -
CAS Number
1160247-92-6 -
Chemical structure
Properties
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Chemical name
1-[(4-Methoxyphenyl)methyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione -
Molecular weight
351.28 -
Molecular formula
C17H12F3NO4 -
PubChem identifier
42633508 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
FC(F)(F)Oc1cc3c(cc1)N(Cc2ccc(OC)cc2)C(=O)C3=O -
Source
Synthetic
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Research areas
