Valspodar (PSC-833), P-glycoprotein inhibitor (ab145870)
Key features and details
- Selective P-glycoprotein inhibitor
- CAS Number: 121584-18-7
- Purity: > 99%
- Soluble in DMSO to 4 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Valspodar (PSC-833), P-glycoprotein inhibitor -
Description
Selective P-glycoprotein inhibitor -
Alternative names
- PSC833
-
Biological description
Selective P-glycoprotein inhibitor. Cyclosporin (ab143599) analog. Shows chemosensitizing effects in vivo. Orally active.
-
Purity
> 99% -
CAS Number
121584-18-7 -
Chemical structure
Properties
-
Chemical name
6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A -
Molecular weight
1214.64 -
Molecular formula
C63H111N11O12 -
PubChem identifier
5281884 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 4 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C/C=C/C[C@@H](C)C(=O)[C@H]1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C(C)C -
Source
Synthetic