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URB 597, FAAH inhibitor (ab120668)

Key features and details

  • Potent and selective FAAH inhibitor
  • CAS Number: 546141-08-6
  • Purity: > 98%
  • Soluble in ethanol to 25 mM (with warming)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    URB 597, FAAH inhibitor
  • Description

    Potent and selective FAAH inhibitor
  • Biological description

    Potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC50 values are 4.6 nM in brain membranes and 0.5 nM in neurons). Causes accumulation of anandamide. Displays anxiolytic, antidepressant, antinociceptive and analgesic effect.

  • Purity

    > 98%
  • General notes

    This compound has been found to be unstable in DMSO even at room temperature.

  • CAS Number

    546141-08-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester
  • Molecular weight

    338.41
  • Molecular formula

    C20H22N2O3
  • Storage instructions

    Store at +4°C. Please see notes section. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 25 mM (with warming)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Cannabinoid Receptor
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Cannabinoid
    • Other
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Hydrolase
    • Inhibitors
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipid metabolism
    • Biochemicals
    • Research Area
    • Addiction
    • Cannabinoid
    • Other
    • Biochemicals
    • Research Area
    • Obesity
    • Cannabinoid
    • Other
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Cannabinoid
    • Other

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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