U-46619, Thromboxane A2 agonist (ab144540)
Key features and details
- Potent thromboxane A2 agonist
- CAS Number: 56985-40-1
- Purity: > 98%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
U-46619, Thromboxane A2 agonist -
Description
Potent thromboxane A2 agonist -
Biological description
Potent thromboxane A2 agonist (EC50 = 35 nM). Activates p38, ERK-1 and ERK-2. Induces platelet aggregation and shows vasoconstrictive effects in vivo. -
Purity
> 98% -
CAS Number
56985-40-1 -
Chemical structure
Properties
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Chemical name
(Z)-7-[(1S,2S,3R,4R)-3-[(E,3S)-3-Hydroxyoct-1-enyl]-5-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid -
Molecular weight
350.50 -
Molecular formula
C21H34O4 -
PubChem identifier
5311493 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@H]2C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)CO2)O -
Source
Synthetic
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Research areas