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Cardiovascular Atherosclerosis Thrombosis Platelets

U-46619, Thromboxane A2 agonist (ab144540)

Price and availability

77 059 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Potent thromboxane A2 agonist
  • CAS Number: 56985-40-1
  • Purity: > 98%
  • Soluble in ethanol and in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    U-46619, Thromboxane A2 agonist
  • Description

    Potent thromboxane A2 agonist
  • Biological description

    Potent thromboxane A2 agonist (EC50 = 35 nM). Activates p38, ERK-1 and ERK-2. Induces platelet aggregation and shows vasoconstrictive effects in vivo.
  • Purity

    > 98%
  • CAS Number

    56985-40-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (Z)-7-[(1S,2S,3R,4R)-3-[(E,3S)-3-Hydroxyoct-1-enyl]-5-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid
  • Molecular weight

    350.50
  • Molecular formula

    C21H34O4
  • PubChem identifier

    5311493
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol and in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCC[C@@H](/C=C/[C@H]1[C@H]2C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)CO2)O
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Blood
    • Platelets
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
    • Platelets
    • Cardiovascular
    • Vasculature
    • Vasoconstriction
    • Other
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Types of disease
    • Heart disease

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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