Troleandomycin, Cytochrome P450 3A4 inhibitor. (ab141568)
Key features and details
- Macrolide antibiotic. Cytochrome P450 3A4 inhibitor.
- CAS Number: 2751-09-9
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Troleandomycin, Cytochrome P450 3A4 inhibitor. -
Description
Macrolide antibiotic. Cytochrome P450 3A4 inhibitor. -
Alternative names
- Cyclamycin
- Evramicina
- Oleandocetine
see all -
Biological description
Macrolide antibiotic. Cytochrome P450 3A4 inhibitor. Inhibits NO release from Glycerol trinitrate (GTN). Anti-asthmatic activity in vivo.
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Purity
> 98% -
CAS Number
2751-09-9 -
Chemical structure
Properties
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Chemical name
[(3R,5S,6S,7R,8S,9R,12R,13S,14R,15R)-6-[(2S,3R,4S,6R)-3-Acetyloxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-8-[(2R,4S,5S,6S)-5-acetyloxy-4-methoxy-6-methyloxan-2-yl]oxy-5,7,9,12,13,15-hexamethyl-10,16-dioxo-1,11-dioxaspiro[2.13]hexadecan-14-yl] acetate -
Molecular weight
814.00 -
Molecular formula
C41H67NO15 -
PubChem identifier
17675 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC(C(C(O1)OC2C(CC3(CO3)C(=O)C(C(C(C(OC(=O)C(C(C2C)OC4CC(C(C(O4)C)OC(=O)C)OC)C)C)C)OC(=O)C)C)C)OC(=O)C)N(C)C -
Source
Synthetic
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Research areas
