Trimethylapigenin, KV1.5 and KV11.1 (hERG) channel blocker (ab145558)
Key features and details
- KV1.5 and KV11.1 (hERG) channel blocker. CFTR channel blocker.
- CAS Number: 5631-70-9
- Purity: > 96%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Trimethylapigenin, KV1.5 and KV11.1 (hERG) channel blocker -
Description
KV1.5 and KV11.1 (hERG) channel blocker. CFTR channel blocker. -
Biological description
KV1.5 and KV11.1 (hERG) channel blocker (IC50 values are 8 and 30 μM for KV1.5 and hERG respectively). CFTR channel blocker. Putative anti-atrial fibrillation agent. Active in vivo. -
Purity
> 96% -
CAS Number
5631-70-9 -
Chemical structure
Properties
-
Chemical name
5,7-Dimethoxy-2-(4-methoxyphenyl)chromen-4-one -
Molecular weight
312.32 -
Molecular formula
C18H16O5 -
PubChem identifier
79730 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
COC1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC)OC -
Source
Synthetic
-
Research areas