Tie2 kinase inhibitor, ATP-binding site-targeting Tie2 kinase inhibitor. Cell-permeable. (ab141270)
Key features and details
- Potent, reversible and selective ATP-binding site-targeting Tie2 kinase inhibitor. Cell-permeable.
- CAS Number: 948557-43-5
- Purity: > 99%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tie2 kinase inhibitor, ATP-binding site-targeting Tie2 kinase inhibitor. Cell-permeable. -
Description
Potent, reversible and selective ATP-binding site-targeting Tie2 kinase inhibitor. Cell-permeable. -
Biological description
Potent, reversible and selective ATP-binding site-targeting Tie2 kinase inhibitor (IC50 = 250 nM). Anti- angiogenesis agent. Active in vivo and in vivo. Cell-permeable.
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Purity
> 99% -
CAS Number
948557-43-5 -
Chemical structure
Properties
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Chemical name
4-[4-(6-Methoxy-2-naphthalenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine -
Molecular weight
439.53 -
Molecular formula
C26H21N3O2S -
PubChem identifier
23625762 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CS(=O)c1ccc(cc1)c2nc(c(n2)c3cc4ccc(OC)cc4cc3)c5ccncc5 -
Source
Synthetic
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Research areas
