Glucagon (19-29) (human), Ca2+/Mg2+-ATPase inhibitor (ab142303)
Key features and details
- C-terminal fragment of Glucagon. Potent Ca2+/Mg2+-ATPase inhibitor.
- CAS Number: 64790-15-4
- Purity: > 95%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Glucagon (19-29) (human), Ca2+/Mg2+-ATPase inhibitor -
Description
C-terminal fragment of Glucagon. Potent Ca2+/Mg2+-ATPase inhibitor. -
Alternative names
- Miniglucagon
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Biological description
C-terminal fragment of Glucagon. Potently inhibits secretagogue-induced insulin secretion in β-cells (IC502+/Mg2+-ATPase activity in liver plasma membranes (IC50 = 0.75 nM). May also contribute to the positive inotropic effect of glucagon in cardiac cells by amplifying the cytosolic Ca2+ signal. -
Purity
> 95% -
CAS Number
64790-15-4 -
Chemical structure
Properties
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Molecular weight
1352.54 -
Molecular formula
C61H89N15O18S -
Sequence
AQDFVQWLMNT -
PubChem identifier
3080901 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
- Biochemicals
- Pharmacology
- Receptors & Transporters
- Peptide Receptors
- Glucagon and Related Receptors
- Agonists
- Biochemicals
- Pharmacology
- Receptors & Transporters
- Enzyme-Linked Receptors
- Receptor tyrosine kinases
- Insulin
