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Cardiovascular Heart Cardiac arrhythmias

Tacrine hydrochloride, cholinesterase inhibitor  (ab255916)

Key features and details

  • Potent cholinesterase inhibitor
  • CAS Number: 1684-40-8
  • Soluble in DMSO to 100 mM, ethanol to 100 mM and water to 100 mM

  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Tacrine hydrochloride, cholinesterase inhibitor 
  • Description

    Potent cholinesterase inhibitor
  • Biological description

    Potent cholinesterase inhibitor (IC50 = 125 nM). Also inhibits butyryl cholinesterase. Cognition enhancer in vivo. Selectively blocks potassium channels in the central nervous system. Increases release of acetylcholine. Prolongs the action potential of presynaptic cholinergic neurons.

  • CAS Number

    1684-40-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1,2,3,4-tetrahydroacridin-9-amine hydrochloride

  • Molecular weight

    234.73
  • Molecular formula

    C13H14N2.HCl
  • PubChem identifier

    2723754
  • Storage instructions

    Shipped at Room Temperature. Store at -20°C long term.
  • Solubility overview

    Soluble in DMSO to 100 mM, ethanol to 100 mM and water to 100 mM

  • Handling

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CCC2=NC3=CC=CC=C3C(=C2C1)N.Cl
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Heart
    • Cardiac arrhythmias

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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