Territrem B, AChE inhibitor (ab144370)
Key features and details
- Potent and selective irreversible AChE inhibitor
- CAS Number: 70407-20-4
- Purity: > 95%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Territrem B, AChE inhibitor -
Description
Potent and selective irreversible AChE inhibitor -
Biological description
Potent and selective irreversible AChE inhibitor (IC50 = 8 nM). Binds to the P-site and A-site of AChE. Potentiates ACh-induced neuronal current. Shows antifungal and cholinergic effects in vivo. Orally active. -
Purity
> 95% -
CAS Number
70407-20-4 -
Chemical structure
Properties
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Chemical name
(4aR,6aR,12aS,12bS)-4a,6,6a,12,12a,12b-Hexahydro-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-trimethoxyphenyl)-4H,11H-naphtho(2,1-b)pyrano(3,4-e)pyran-1,11(5H)-dione -
Molecular weight
526.57 -
Molecular formula
C29H34O9 -
PubChem identifier
114734 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@]12CC[C@@]3([C@@]([C@]1(CC4=C(O2)C=C(OC4=O)C5=CC(=C(C(=C5)OC)OC)OC)O)(C(=O)C=CC3(C)C)C)O -
Source
Synthetic
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Research areas
