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SU 1498, VEGFR2 inhibitor (ab141447)

Price and availability

150 768 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Selective VEGFR2 inhibitor
  • CAS Number: 168835-82-3
  • Purity: > 99%
  • Soluble in ethanol to 100 mM and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SU 1498, VEGFR2 inhibitor
  • Description

    Selective VEGFR2 inhibitor
  • Purity

    > 99%
  • General notes

    It is important to note that this product has been reported to be unstable under a variety of conditions. In addition to being unstable to light and air after extended periods of time, this product is extremely unstable in polar solvents such as DMSO. Within 1 hour a DMSO solution showed signs of decomposition. We therefore recommend this material is only stored as the solid form at -20°C (or below), with the exclusion of light and air, and any solutions are made up fresh and used immediately

  • CAS Number

    168835-82-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (E)-2-Cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide
  • Molecular weight

    390.52
  • Molecular formula

    C25H30N2O2
  • PubChem identifier

    5941539
  • Storage instructions

    Store at -20°C. Please see notes section. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Soluble in ethanol to 100 mM and in DMSO to 100 mM
  • Handling

    Unstable; make up solutions fresh and use immediately.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)C1=CC(=CC(=C1O)C(C)C)C=C(C#N)C(=O)NCCCC2=CC=CC=C2
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Growth Factors
    • VEGF
    • VEGF Receptors
    • Microbiology
    • Interspecies Interaction
    • Host Virus Interaction
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Synthesis
    • Topoisomerases
    • Signal Transduction
    • Protein Phosphorylation
    • Tyrosine Kinases
    • Receptor Tyrosine Kinases
    • Signal Transduction
    • Growth Factors/Hormones
    • VEGF
    • Stem Cells
    • Hematopoietic Progenitors
    • Surface Molecules
    • Cancer
    • Growth factors
    • VEGF
    • Cancer
    • Invasion/microenvironment
    • Angiogenesis
    • Angiogenic growth factors
    • Cancer
    • Oncoproteins/suppressors
    • Oncoproteins
    • Growth factor receptors
    • Stem Cells
    • Endothelial Progenitors
    • Endothelial Markers
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Enzyme-Linked Receptors
    • Receptor tyrosine kinases
    • VEGFR
    • Cardiovascular
    • Cardiovascular Markers
    • Cell Markers
    • Endothelial Cells
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Growth factors
    • VEGFR
    • Biochemicals
    • Research Area
    • Cancer
    • Apoptosis & cell cycle
    • Growth factors
    • VEGFR
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Tyrosine Kinase
    • Receptor Tyrosine Kinase
    • VEGFR
    • Biochemicals
    • Pharmacology
    • Signaling
    • Stem Cells
    • Growth factors
    • Biochemicals
    • Research Area
    • Stem Cells
    • Growth factors
    • Cardiovascular
    • Angiogenesis
    • Endothelial Cell Markers

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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