SU 11274, Met inhibitor (ab142159)
Key features and details
- Potent, selective cell-permeable Met inhibitor
- CAS Number: 658084-23-2
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SU 11274, Met inhibitor -
Description
Potent, selective cell-permeable Met inhibitor -
Biological description
Potent, selective Met inhibitor (IC50 = 20 nM). Anticancer activity in vivo. Cell-permeable. -
Purity
> 98% -
CAS Number
658084-23-2 -
Chemical structure
Properties
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Chemical name
(3Z)-N-(3-Chlorophenyl)-3-[[3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl]methylidene]-N-methyl-2-oxo-1H-indole-5-sulfonamide -
Molecular weight
568.09 -
Molecular formula
C28H30ClN5O4S -
PubChem identifier
9549297 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O -
Source
Synthetic
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Research areas
