STF-083010, IRE1alpha endonuclease inhibitor (ab146176)
Key features and details
- Selective IRE1α endonuclease inhibitor
- CAS Number: 307543-71-1
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
STF-083010, IRE1alpha endonuclease inhibitor -
Description
Selective IRE1α endonuclease inhibitor -
Biological description
Selective IRE1α endonuclease inhibitor. Dose dependently inhibits XBP-1 splicing. Shows cancer cell selective cytotoxic and cytostatic antiproliferative effects. Shows antitumor effects in vivo. -
CAS Number
307543-71-1 -
Chemical structure
Properties
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Chemical name
N-[(Z)-(2-Oxonaphthalen-1-ylidene)methyl]thiophene-2-sulfonamide -
Molecular weight
317.38 -
Molecular formula
C15H11NO3S2 -
PubChem identifier
6537512 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C\2C(=C1)C=CC(=O)/C2=C\NS(=O)(=O)C3=CC=CS3 -
Source
Synthetic
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Research areas