Sterigmatocystin, DNA synthesis inhibitor (ab143698)
Key features and details
- DNA synthesis inhibitor. Mycotoxin.
- CAS Number: 10048-13-2
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Sterigmatocystin, DNA synthesis inhibitor -
Description
DNA synthesis inhibitor. Mycotoxin. -
Biological description
DNA synthesis inhibitor. Mycotoxin. p21 inhibitor. Potent mutagenic agent. Induces sister chromatid exchanges. Induces liver and kidney necrosis. Inhibits orotic acid incorporation into nuclear RNA. Induces hepatomas and pulmonary tumours in vivo. Orally active. -
Purity
> 98% -
CAS Number
10048-13-2 -
Chemical structure
Properties
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Chemical name
(3aR-cis)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one -
Molecular weight
324.28 -
Molecular formula
C18H12O6 -
PubChem identifier
5284457 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C2C(=C3C4C=COC4OC3=C1)OC5=C(C2=O)C(=CC=C5)O -
Source
Synthetic
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Research areas