SCH-58261, A2A antagonist (ab120439)
Key features and details
- Potent, highly selective A2A antagonist
- CAS Number: 160098-96-4
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SCH-58261, A2A antagonist -
Description
Potent, highly selective A2A antagonist -
Biological description
Potent, highly selective A2A receptor antagonist. (Ki values are 1-2, 289 and >10000 nM at A2A, A1 and A3 receptors, respectively). Displays therapeutic effects in animal Parkinson's models and elicits locomotor sensitization in vivo.
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Purity
> 99% -
CAS Number
160098-96-4 -
Chemical structure
Properties
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Chemical name
2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine -
Molecular weight
345.36 -
Molecular formula
C18H15N7O -
PubChem identifier
176408 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Nc3nc2c(cnn2CCc1ccccc1)c4nc(nn34)c5ccco5 -
Source
Synthetic
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Research areas
