SC-560, COX-1 inhibitor (ab120649)
Key features and details
- Highly selective COX-1 inhibitor
- CAS Number: 188817-13-2
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SC-560, COX-1 inhibitor -
Description
Highly selective COX-1 inhibitor -
Biological description
Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active.
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Purity
> 99% -
CAS Number
188817-13-2 -
Chemical structure
Properties
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Chemical name
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole -
Molecular weight
352.74 -
Molecular formula
C17H12ClF3N2O -
PubChem identifier
4306515 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl -
Source
Synthetic
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Research areas
