SB 408124, non-peptide OX1 antagonist (ab141105)
Key features and details
- Selective, non-peptide OX1 antagonist
- CAS Number: 288150-92-5
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB 408124, non-peptide OX1 antagonist -
Description
Selective, non-peptide OX1 antagonist -
Biological description
Selective, non-peptide orexin receptor 1 (OX1) antagonist (Ki = 26.9 nM). Displays 50-fold selectivity over OX2 (Kb values are 21.7 and 1405 nM for OX1 and OX2, respectively).
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Purity
> 98% -
CAS Number
288150-92-5 -
Chemical structure
Properties
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Chemical name
N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea -
Molecular weight
356.37 -
Molecular formula
C19H18F2N4O -
PubChem identifier
4331799 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)c1ccc(cc1)NC(=O)Nc2cc(C)nc3c(F)cc(F)cc23 -
Source
Synthetic
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Research areas
