Saikosaponin D, glucocorticoid receptor agonist (ab143545)
Key features and details
- Glucocorticoid receptor agonist. COX-2 and iNOS inhibitor.
- CAS Number: 20874-52-6
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Saikosaponin D, glucocorticoid receptor agonist -
Description
Glucocorticoid receptor agonist. COX-2 and iNOS inhibitor. -
Biological description
Glucocorticoid receptor agonist. COX-2 and iNOS inhibitor. Saikosaponin A (ab143543) epimer. Inhibits NF-κB, TNF-α, IL-1β and IL-6. Inhibits apoptosis. Shows anti-inflammatory and antiallergic effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
20874-52-6 -
Chemical structure
Properties
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Chemical name
(3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl-6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside -
Molecular weight
780.98 -
Molecular formula
C42H68O13 -
PubChem identifier
107793 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O -
Source
Synthetic
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Research areas
