(R,S)-Sulforaphane, antagonist of Ah receptor (ab141969)
Key features and details
- Potent, non-competitive antagonist of Ah receptor
- CAS Number: 4478-93-7
- Purity: > 99%
Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(R,S)-Sulforaphane, antagonist of Ah receptor -
Description
Potent, non-competitive antagonist of Ah receptor -
Biological description
Potent, non-competitive antagonist of the aryl hydrocarbon (Ah) receptor (IC50 = 1 μM). Isothiocyanate. Induces epoxide hydrolase. Anticarcinogenic. Active in vivo and in vitro. -
Purity
> 99% -
General notes
This compound is a neat liquid at room temperature, clear to slightly yellow in color. It is not dissolved in solvent. In small quantities the material will coat the sides of the ampule it is shipped in and may appear to be invisible, or it may be trapped in the tip of the ampule. Wash the upper and lower parts of the ampule with solvent to ensure all of the material is obtained.
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CAS Number
4478-93-7 -
Chemical structure

Properties
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Chemical name
1-Isothiocyanato-4-methylsulfinylbutane
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Molecular weight
177.29 -
Molecular formula
C6H11NOS2 -
PubChem identifier
5350 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CS(=O)CCCCN=C=S -
Source
Synthetic
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Research areas