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Neuroscience Neurotransmission Nitric Oxide NOS

(R,S)-Sulforaphane, antagonist of Ah receptor (ab141969)

Price and availability

113 913 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Potent, non-competitive antagonist of Ah receptor
  • CAS Number: 4478-93-7
  • Purity: > 99%
  • Soluble in DMSO to 100 mM

  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    (R,S)-Sulforaphane, antagonist of Ah receptor
  • Description

    Potent, non-competitive antagonist of Ah receptor
  • Biological description

    Potent, non-competitive antagonist of the aryl hydrocarbon (Ah) receptor (IC50 = 1 μM). Isothiocyanate. Induces epoxide hydrolase. Anticarcinogenic. Active in vivo and in vitro.
  • Purity

    > 99%
  • General notes

    This compound is a neat liquid at room temperature, clear to slightly yellow in color. It is not dissolved in solvent. In small quantities the material will coat the sides of the ampule it is shipped in and may appear to be invisible, or it may be trapped in the tip of the ampule. Wash the upper and lower parts of the ampule with solvent to ensure all of the material is obtained.

  • CAS Number

    4478-93-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Isothiocyanato-4-methylsulfinylbutane

  • Molecular weight

    177.29
  • Molecular formula

    C6H11NOS2
  • PubChem identifier

    5350
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CS(=O)CCCCN=C=S
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Nitric Oxide
    • NOS
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Other factors
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Cell Biology
    • Other Antibodies
    • Oxidative Stress
    • Cardiovascular
    • Heart
    • Cardiac metabolism
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Cancer
    • Cancer Metabolism
    • Cellular metabolic process
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nuclear Receptors
    • Aryl hydrocarbon receptors
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Mitochondrial Biogenesis
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Nucleotide metabolism
    • Molecular processes
    • Mitochondrial transcription
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Metabolism
    • Pathways and Processes
    • Redox metabolism
    • Oxidative stress
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • General

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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