(R,R)-Hymeglusin, antibiotic agent (ab144274)
Key features and details
- β-Lactone antibiotic and antifungal agent
- CAS Number: 29066-42-0
- Purity: > 95%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Scopulariopsis sp.
Overview
-
Product name
(R,R)-Hymeglusin, antibiotic agent -
Description
β-Lactone antibiotic and antifungal agent -
Alternative names
- Antibiotic 1233A
- Antibiotic F 244
- Antibiotic L-659-699
-
Biological description
β-Lactone antibacterial and antifungal agent. Specific irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (IC50 = 0.12 µM) in vitro and in vivo.
See similar compound -
Purity
> 95% -
CAS Number
29066-42-0 -
Chemical structure
Properties
-
Chemical name
(2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid -
Molecular weight
324.41 -
Molecular formula
C18H28O5 -
PubChem identifier
6440895 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C[C@H](CCCC[C@@H]1[C@H](C(=O)O1)CO)C/C(=C/C(=C/C(=O)O)/C)/C -
Source
Scopulariopsis sp.
