Rofecoxib, COX-2 inhibitor NSAID (ab146172)
Key features and details
- Selective COX-2 inhibitor. NSAID.
- CAS Number: 162011-90-7
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rofecoxib, COX-2 inhibitor NSAID -
Description
Selective COX-2 inhibitor. NSAID. -
Biological description
Selective COX-2 inhibitor. NSAID. Inhibits prostaglandin biosynthesis. Shows anti-inflammatory, analgesic, and antipyretic effects in vivo. Orally active. Blood-brain barrier permeable. -
CAS Number
162011-90-7 -
Chemical structure
Properties
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Chemical name
3-(4-Methylsulfonylphenyl)-4-phenyl-2H-furan-5-one -
Molecular weight
314.36 -
Molecular formula
C17H14O4S -
PubChem identifier
5090 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3 -
Source
Synthetic
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Research areas