Ro 41-5253, Retinoic acid receptor antagonist (ab141629)
Key features and details
- Potent, selective retinoic acid receptor antagonist
- CAS Number: 144092-31-9
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ro 41-5253, Retinoic acid receptor antagonist -
Description
Potent, selective retinoic acid receptor antagonist -
Biological description
Potent, selective retinoic acid receptor (RAR) antagonist (IC50 values are 60 nM, 2400 nM and 3300 nM for RARα, RARβ and RARγ, respectively). Active in vitro. -
Purity
> 99% -
CAS Number
144092-31-9 -
Chemical structure
Properties
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Chemical name
4-[(E)-2-(7-Heptoxy-4,4-dimethyl-1,1-dioxo-2,3-dihydrothiochromen-6-yl)prop-1-enyl]benzoic acid -
Molecular weight
484.70 -
Molecular formula
C28H36O5S -
PubChem identifier
5312120 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCOC1=CC2=C(C=C1C(=CC3=CC=C(C=C3)C(=O)O)C)C(CCS2(=O)=O)(C)C -
Source
Synthetic
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Research areas
