Rhodadyn™ B10, Negative control for Rhodadyn™ C10 (ab120796)
Key features and details
- Negative control for Rhodadyn™ C10 (ab120795)
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rhodadyn™ B10, Negative control for Rhodadyn™ C10 -
Description
Negative control for Rhodadyn™ C10 (ab120795) -
Biological description
Negative control for Rhodadyn™ C10 (ab120795). Demonstrates no significant inhibition of dynamin I or dynamin II in vitro GTPase activity at concentrations up to 300 μM and has no effect on clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture.
Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012). -
Purity
> 98% -
General notes
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd. -
Chemical structure
Properties
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Chemical name
(5Z)-5-[4-[3-(Dimethylamino)propoxy]benzylidene]-2-thioxo-1,3-thiazolidin-4-one -
Molecular weight
322.44 -
Molecular formula
C15H18N2O2S2 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
