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Neuroscience Neurology process Neurogenesis

Recombinant mouse Wnt3a protein (ab205620)

Key features and details

  • Expression system: CHO cells
  • Purity: > 80% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant mouse Wnt3a protein
    See all Wnt3a proteins and peptides
  • Biological activity

    Biological Activity: Wnt3a can induce β-catenin mediated response in a TCF/LEF reporter gene luciferase assay.

  • Purity

    > 80 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells
  • Accession

    P27467
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVP KQLRFCRNYVEIMPSVAEGVKAGIQECQ HQFRGRRWNCTTVSNSLAIF GPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGE GWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASH MHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRE SRGWVETLRP RYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRT CNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVY DVHTCK
    • Predicted molecular weight

      39 kDa
    • Amino acids

      1 to 352
  • Specifications

    Our Abpromise guarantee covers the use of ab205620 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      Constituents: 99% PBS, 1% CHAPS

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    General Info

    • Alternative names

      • Protein Wnt 3a Precursor
      • Protein Wnt-3a
      • Wingless type MMTV integration site family member 3A
      • Wnt 3a
      • wnt3a
      • WNT3A protein
      • WNT3A_HUMAN
      see all
    • Function

      Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
    • Tissue specificity

      Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.
    • Sequence similarities

      Belongs to the Wnt family.
    • Cellular localization

      Secreted > extracellular space > extracellular matrix.
    • Target information above from: UniProt accession P56704 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab205620? Please let us know so that we can cite the reference in this datasheet.

    ab205620 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Protein Wnt 3a Precursor
    • Protein Wnt-3a
    • Wingless type MMTV integration site family member 3A

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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