Recombinant Mouse ROR1 protein (Fc Chimera) (ab221220)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
Preparation and Storage
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Alternative names
- dJ537F10.1
- Inactive tyrosine protein kinase transmembrane receptor ROR1
- MGC99659
see all -
Function
Tyrosine-protein kinase receptor whose role is not yet clear. -
Tissue specificity
Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
Contains 1 FZ (frizzled) domain.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 kringle domain.
Contains 1 protein kinase domain. -
Developmental stage
Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Mouse ROR1 protein (Fc Chimera) (ab221220)
SDS-PAGE of reduced ab221220 stained overnight with Coomassie Blue. The protein migrates as 76-96 kDa due to glycosylation.
