Antibodies, Proteins, Kits and Reagents for Life Science

Recombinant mouse MIP-3 beta/CCL19 protein (Active) (ab243280)

Key features and details

Expression system: Escherichia coli
Endotoxin level:
Active: Yes
Suitable for: SDS-PAGE, Functional Studies, HPLC

Alternative names
- Beta chemokine exodus 3
- Beta-chemokine exodus-3
- C C chemokine ligand 19
- C-C motif chemokine 19
- CC chemokine ligand 19
- CCL 19
- CCL19
- CCL19_HUMAN
- Chemokine (C C motif) ligand 19
- Chemokine (CC motif) ligand 19
- Chemokine C C Motif Ligand 19
- Chemokine CC Motif Ligand 19
- CK beta 11
- CK beta-11
- CKb 11
- CKb11
- EBI 1 ligand chemokine
- EBI1 ligand chemokine
- ELC
- Epstein-Barr virus-induced molecule 1 ligand chemokine
- Exodus 3
- Exodus3
- Macrophage inflammatory protein 3 beta
- MGC34433
- MIP 3 beta
- MIP 3B
- MIP-3-beta
- MIP-3b
- MIP3 beta
- MIP3B
- OTTHUMP00000000531
- SCYA 19
- SCYA19
- Small inducible cytokine A19
- Small inducible cytokine subfamily A (Cys Cys) member 1
- Small-inducible cytokine A19
see all
Function

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
Tissue specificity

Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.
Cellular localization

Secreted.
Target information above from: UniProt accession Q99731 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant mouse MIP-3 beta/CCL19 protein (Active) (ab243280)

SDS Page analysis of MIP-3 beta/CCL19 with ab243280.

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