Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human MIP-3 beta/CCL19 protein (ab9832)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

Description

  • Product name

    Recombinant human MIP-3 beta/CCL19 protein
    See all MIP-3 beta/CCL19 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      11 kDa

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9832 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized

      • Additional notes

        The biological activity of this product was determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

         This product was previously labelled as Macrophage Inflammatory Protein 3 beta

         

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • Beta chemokine exodus 3
        • Beta-chemokine exodus-3
        • C C chemokine ligand 19
        • C-C motif chemokine 19
        • CC chemokine ligand 19
        • CCL 19
        • CCL19
        • CCL19_HUMAN
        • Chemokine (C C motif) ligand 19
        • Chemokine (CC motif) ligand 19
        • Chemokine C C Motif Ligand 19
        • Chemokine CC Motif Ligand 19
        • CK beta 11
        • CK beta-11
        • CKb 11
        • CKb11
        • EBI 1 ligand chemokine
        • EBI1 ligand chemokine
        • ELC
        • Epstein-Barr virus-induced molecule 1 ligand chemokine
        • Exodus 3
        • Exodus3
        • Macrophage inflammatory protein 3 beta
        • MGC34433
        • MIP 3 beta
        • MIP 3B
        • MIP-3-beta
        • MIP-3b
        • MIP3 beta
        • MIP3B
        • OTTHUMP00000000531
        • SCYA 19
        • SCYA19
        • Small inducible cytokine A19
        • Small inducible cytokine subfamily A (Cys Cys) member 1
        • Small-inducible cytokine A19
        see all

      • Function

        May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.

      • Tissue specificity

        Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.

      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab9832? Please let us know so that we can cite the reference in this datasheet.

    ab9832 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Beta chemokine exodus 3
      • Beta-chemokine exodus-3
      • C C chemokine ligand 19
      • C-C motif chemokine 19
      • CC chemokine ligand 19
      • CCL 19
      • CCL19
      • CCL19_HUMAN
      • Chemokine (C C motif) ligand 19
      • Chemokine (CC motif) ligand 19
      • Chemokine C C Motif Ligand 19
      • Chemokine CC Motif Ligand 19
      • CK beta 11
      • CK beta-11
      • CKb 11
      • CKb11
      • EBI 1 ligand chemokine
      • EBI1 ligand chemokine
      • ELC
      • Epstein-Barr virus-induced molecule 1 ligand chemokine
      • Exodus 3
      • Exodus3
      • Macrophage inflammatory protein 3 beta
      • MGC34433
      • MIP 3 beta
      • MIP 3B
      • MIP-3-beta
      • MIP-3b
      • MIP3 beta
      • MIP3B
      • OTTHUMP00000000531
      • SCYA 19
      • SCYA19
      • Small inducible cytokine A19
      • Small inducible cytokine subfamily A (Cys Cys) member 1
      • Small-inducible cytokine A19
      see all

    • Function

      May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.

    • Tissue specificity

      Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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