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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant Mouse Macrophage Inflammatory Protein 3 alpha (ab50168)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    Recombinant Mouse Macrophage Inflammatory Protein 3 alpha
    See all Macrophage Inflammatory Protein 3 alpha proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab50168 purity was assessed also by HPLC. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM
    • Amino acids

      28 to 97
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50168 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

      • Reconstitution
        Reconsitute to 1mg/ml in distilled water.

      General Info

      • Alternative names

        • Beta chemokine exodus 1
        • Beta-chemokine exodus-1
        • C C motif chemokine ligand 20
        • C-C motif chemokine 20
        • CC chemokine LARC
        • Ccl20
        • CCL20(2-70)
        • CCL20_HUMAN
        • Chemokine (C C motif) ligand 20
        • Chemokine C-C motif chemokine 20
        • Chemokine CC motif ligand 20
        • CKb4
        • Exodus
        • Exodus 1
        • LARC
        • Liver and activation regulated chemokine
        • Liver and activation-regulated chemokine
        • Macrophage inflammatory protein 3 alpha
        • MIP 3 alpha
        • MIP 3A
        • MIP-3-alpha
        • MIP-3a
        • MIP3 alpha
        • MIP3A
        • SCYA20
        • Small inducible cytokine A20
        • Small inducible cytokine subfamily A (Cys Cys) member 20
        • Small-inducible cytokine A20
        • ST38
        see all
      • Function

        Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
      • Tissue specificity

        Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.
      • Post-translational
        modifications

        C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P78556 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab50168? Please let us know so that we can cite the reference in this datasheet.

    ab50168 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Beta chemokine exodus 1
      • Beta-chemokine exodus-1
      • C C motif chemokine ligand 20
      • C-C motif chemokine 20
      • CC chemokine LARC
      • Ccl20
      • CCL20(2-70)
      • CCL20_HUMAN
      • Chemokine (C C motif) ligand 20
      • Chemokine C-C motif chemokine 20
      • Chemokine CC motif ligand 20
      • CKb4
      • Exodus
      • Exodus 1
      • LARC
      • Liver and activation regulated chemokine
      • Liver and activation-regulated chemokine
      • Macrophage inflammatory protein 3 alpha
      • MIP 3 alpha
      • MIP 3A
      • MIP-3-alpha
      • MIP-3a
      • MIP3 alpha
      • MIP3A
      • SCYA20
      • Small inducible cytokine A20
      • Small inducible cytokine subfamily A (Cys Cys) member 20
      • Small-inducible cytokine A20
      • ST38
      see all
    • Function

      Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
    • Tissue specificity

      Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications

      C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P78556 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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